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Ionotropic glutamate receptor that capabilities being a cation permeable ligand-gated ion channel, gated by L-glutamate as well as the glutamatergic agonist kainic acid. L-glutamate acts as an excitatory neurotransmitter at a lot of synapses within the central nervous program. Binding on the excitatory neurotransmitter L-glutamate induces a conform